Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA4 | P22748 | 3/20 | 0.56 |
| ▸ | CA6 | P23280 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11230186 | 0.78 | CA1 (0.56) | CA1CA2CA4CA6ALOX15 | |
| SCHEMBL11791216 | 0.76 | CA2 (0.53) | CA1CA2CA4CA6ALOX15 | |
| SCHEMBL3299013 | 0.75 | — | — | |
| Tetrabromocatechol SCHEMBL985158 | 0.74 | CA1 (1.00) | CA1CA2CA4CA6ALOX15 | |
| SCHEMBL6436652 | 0.71 | CA1 (0.91) | CA1CA2CA4CA6ALOX15 | |
| SCHEMBL21869868 | 0.71 | ALOX15 (0.62) | CA1CA2CA4CA6ALOX15 | |
| Pentabromophenol SCHEMBL268325 | 0.67 | ALOX15 (1.00) | CA1CA2CA4CA6ALOX15 | |
| SCHEMBL11799145 | 0.67 | TSHR (0.36) | — | |
| Pentabromophenol SCHEMBL11697558 | 0.64 | ALOX15 (0.91) | CA1CA2CA4CA6ALOX15 | |
| SCHEMBL127379 | 0.64 | ALOX15 (0.91) | CA1CA2CA4CA6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877251-B1 | Dry analytical elements for the determination of protein | ORTHO CLINICAL DIAGNOSTICS INC (US) | 2002-11-27 | — | — | EP | disclosed |
| US-6046052-A | FOR SENSITIVE, ACCURATE AND RAPID DETECTION AND QUANTITATION; INCLUDES A POROUS SPREADING LAYER AND ONE OR MORE LAYERS OF INDICATOR DYE, MOLYBDATE SALT, AN ACRYLAMIDE POLYMER TO STABILIZE THE ASSAY AND A SUPPORT | ORTHO CLINICAL DIAGNOSTICS, INC. (US) | 2000-04-04 | — | — | US | disclosed |
| EP-0952451-A1 | Dry analytical elements for the determination of protein | Ortho-Clinical Diagnostics, Inc. (US) | 1999-10-27 | — | — | EP | disclosed |
| EP-0877251-A1 | Dry analytical elements for the determination of protein | Ortho-Clinical Diagnostics, Inc. (US) | 1998-11-11 | — | — | EP | disclosed |