Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL192021 | 0.94 | TSHR (0.44) | TSHRCA1CA2CA4CA7 | |
| Water SCHEMBL1127581 | 0.89 | TSHR (0.41) | TSHRCA1CA2CA4CA7 | |
| Ethane SCHEMBL1001030 | 0.84 | TSHR (0.39) | TSHRCA1CA2CA4CA7 | |
| SCHEMBL11881165 | 0.82 | TSHR (0.44) | TSHRCA1CA2CA4CA7 | |
| SCHEMBL4458254 | 0.78 | TSHR (0.30) | TSHR | |
| Perbromobenzene SCHEMBL27124 | 0.74 | ALDH1A1 (0.50) | TSHRCA1CA2CA4CA6 | |
| SCHEMBL10977615 | 0.74 | LMNA (0.35) | TSHRCA1CA2CA4CA7 | |
| SCHEMBL1686870 | 0.74 | ALOX15 (0.77) | TSHRCA1CA2CA4CA7 | |
| SCHEMBL13429761 | 0.74 | TSHR (0.33) | TSHRCA1CA2CA4CA7 | |
| SCHEMBL395381 | 0.71 | TSHR (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32606-E | USING LIQUID BROMINE AS SOLVENT AND REACTANT | GREAT LAKES CHEMICAL CORPORATION (US) | 1988-02-16 | — | — | US | disclosed |
| US-3965197-A | CATALYTIC | MICHIGAN CHEMICAL CORPORATION (US) | 1976-06-22 | — | — | US | disclosed |