Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NCEH1 | Q6PIU2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11798018 | 0.93 | LMNA (0.51) | LMNASMN1; SMN2NCEH1TDP1L3MBTL1 | |
| SCHEMBL11810433 | 0.87 | LMNA (0.53) | LMNASMN1; SMN2NCEH1TDP1L3MBTL1 | |
| SCHEMBL11832835 | 0.84 | LMNA (0.44) | LMNASMN1; SMN2NCEH1TDP1L3MBTL1 | |
| Lonaprofen SCHEMBL29670159 | 0.82 | NCEH1 (0.56) | LMNASMN1; SMN2NCEH1TDP1L3MBTL1 | |
| Lonaprofen SCHEMBL2109183 | 0.82 | NCEH1 (0.56) | LMNASMN1; SMN2NCEH1TDP1L3MBTL1 | |
| SCHEMBL11804487 | 0.81 | LMNA (0.47) | LMNASMN1; SMN2NCEH1TDP1L3MBTL1 | |
| SCHEMBL11807725 | 0.80 | NCEH1 (0.54) | LMNASMN1; SMN2NCEH1TDP1L3MBTL1 | |
| SCHEMBL11584986 | 0.79 | LMNA (0.50) | LMNASMN1; SMN2NCEH1TDP1L3MBTL1 | |
| SCHEMBL19608990 | 0.77 | GAA (0.61) | LMNASMN1; SMN2NCEH1TDP1L3MBTL1 | |
| SCHEMBL28418683 | 0.76 | TSHR (0.44) | LMNAALDH1A1TP53TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3968145-A | ANALGESIC, ANTIPYRETIC, ANTIPHLOGISTIC | A. MENARINI S.A.S. (IT) | 1976-07-06 | — | — | US | disclosed |