Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | APP | P05067 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19047012 | 0.91 | ALOX5 (0.57) | ALOX5TDP1APPALDH1A1ESR1 | |
| SCHEMBL19047030 | 0.89 | ALOX5 (0.56) | ALOX5TDP1APPESR1ESR2 | |
| SCHEMBL6071507 | 0.88 | ALOX5 (0.52) | ALOX5TDP1APPALDH1A1ESR1 | |
| SCHEMBL490699 | 0.85 | APP (0.76) | ALOX5TDP1APPL3MBTL1ALDH1A1 | |
| SCHEMBL9367557 | 0.84 | TDP1 (0.92) | ALOX5TDP1APPL3MBTL1ALDH1A1 | |
| SCHEMBL490557 | 0.84 | TDP1 (0.72) | ALOX5TDP1APPL3MBTL1ALDH1A1 | |
| SCHEMBL491005 | 0.83 | ALOX5 (1.00) | ALOX5TDP1APPMAPT | |
| SCHEMBL12386503 | 0.83 | ALOX5 (0.49) | ALOX5TDP1APPALDH1A1ESR1 | |
| SCHEMBL17264213 | 0.83 | ALOX5 (0.49) | ALOX5TDP1APPALDH1A1ESR1 | |
| SCHEMBL2045372 | 0.83 | ALOX5 (0.49) | ALOX5TDP1APPALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969530-A | 4-Hydroxy-3,5-di-alkyl-phenyl-propionic acid composition suitable as lipid lowering and anti-diabetic agents | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-07-13 | — | — | US | disclosed |