Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | FABP7 | O15540 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10458826 | 0.89 | ALDH1A1 (0.44) | ALDH1A1ATMHTTMAPTKMT2A | |
| SCHEMBL11403748 | 0.85 | ALDH1A1 (0.37) | ALDH1A1HTTMAPTKMT2AMEN1 | |
| SCHEMBL11394792 | 0.83 | GAA (0.45) | ALDH1A1HTTMAPTGAARAB9A | |
| SCHEMBL11802708 | 0.82 | ALDH1A1 (0.49) | ALDH1A1ATMHTTMAPTKMT2A | |
| SCHEMBL11795802 | 0.76 | ALDH1A1 (0.50) | ALDH1A1ATMHTTMAPTKMT2A | |
| SCHEMBL10458762 | 0.75 | GAA (0.44) | ALDH1A1KMT2AGAAMEN1POLB | |
| SCHEMBL11384979 | 0.74 | — | — | |
| SCHEMBL11398406 | 0.74 | ATM (0.39) | ALDH1A1ATMHTTMAPTKMT2A | |
| SCHEMBL7694064 | 0.73 | ALDH1A1 (0.47) | ALDH1A1ATMHTTMAPTKMT2A | |
| SCHEMBL11387657 | 0.72 | ALDH1A1 (0.46) | ALDH1A1ATMHTTMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962224-A | CHEMICAL INTERMEDIATES FOR ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-06-08 | — | — | US | disclosed |