Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10458826 | 0.87 | ALDH1A1 (0.44) | GAAALDH1A1KMT2A | |
| SCHEMBL10458760 | 0.82 | GAA (0.48) | GAAPOLBELANEALDH1A1SMN1; SMN2 | |
| SCHEMBL19955268 | 0.78 | GAA (0.47) | GAAPOLBELANEALDH1A1SMN1; SMN2 | |
| SCHEMBL11805263 | 0.78 | CYP3A4 (0.36) | GAAPOLBALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL15549899 | 0.77 | ELANE (0.54) | GAAELANEHSD17B10KLK1TP53 | |
| SCHEMBL1239037 | 0.77 | KYNU (0.55) | GAAELANEALDH1A1KLK1TP53 | |
| SCHEMBL26854257 | 0.77 | KYNU (0.55) | GAAELANEALDH1A1KLK1TP53 | |
| SCHEMBL11814274 | 0.76 | CYP3A4 (0.37) | GAAPOLBALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7282986 | 0.76 | POLB (0.49) | GAAPOLBELANEALDH1A1SMN1; SMN2 | |
| SCHEMBL3434848 | 0.75 | ELANE (0.47) | GAAELANEKLK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4957912-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1990-09-18 | — | — | US | disclosed |
| US-4226866-A | BACTERICIDES, ACYLATION | MERCK & CO., INC. (US) | 1980-10-07 | — | — | US | disclosed |