SCHEMBL11803000

SCHEMBL11803000

CC(C)Nc1ccc(NCCc2ccccc2)c2c1C(=O)c1cccc(O)c1C2=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.59
RAB9A P51151 3/20 0.59
MTOR P42345 2/20 0.59
SIRT2 Q8IXJ6 1/20 0.59
MEN1 O00255 6/20 0.47
KMT2A Q03164 6/20 0.47
BLM P54132 4/20 0.47
NSD2 O96028 3/20 0.47
POLB P06746 3/20 0.47
RXFP1 Q9HBX9 1/20 0.47
P2RY4 P51582 1/20 0.44
TOP2B Q02880 1/20 0.43
LMNA P02545 5/20 0.43
MAPK1 P28482 4/20 0.43
MAPT P10636 3/20 0.43
TDP1 Q9NUW8 3/20 0.43
NPSR1 Q6W5P4 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
ELANE P08246 3/20 0.43
CTSG P08311 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11804465 0.84 MAOA (0.59) MEN1KMT2ABLMPOLBLMNA
SCHEMBL15292783 0.84 CYP19A1 (0.47) NPC1RAB9AMTORSIRT2MEN1
SCHEMBL11799748 0.82 MAOA (0.47) NPC1RAB9AMTORSIRT2MEN1
SCHEMBL13226291 0.81 CYP19A1 (0.44) NPC1RAB9AMTORSIRT2MEN1
SCHEMBL11059596 0.80 RAB9A (0.77) NPC1RAB9AMTORSIRT2MEN1
SCHEMBL11808618 0.80 MAPT (0.50) NPC1RAB9AMEN1KMT2AP2RY4
SCHEMBL11802992 0.80 MAOA (0.47) RAB9AMEN1KMT2ABLMPOLB
SCHEMBL11795891 0.78 MAOA (0.61) RAB9AMEN1KMT2ABLMPOLB
SCHEMBL11795236 0.77 MEN1 (0.54) RAB9AMEN1KMT2ABLMPOLB
SCHEMBL11524878 0.77 MAOA (0.50) MEN1KMT2ABLMPOLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3980677-A Anthraquinone dyestuffs containing sulphonic acid groups BAYER AKTIENGESELLSCHAFT (DT) 1976-09-14 US disclosed