Rafoxanide

Rafoxanide

SCHEMBL118031

O=C(Nc1ccc(Oc2ccc(Cl)cc2)c(Cl)c1)c1cc(I)cc(I)c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PNLIP P16233 14/20 1.00
MEN1 O00255 1/20 1.00
HSPD1 P10809 1/20 1.00
PIK3CA P42336 1/20 1.00
HTT P42858 1/20 1.00
BLM P54132 1/20 1.00
HSPE1 P61604 1/20 1.00
KMT2A Q03164 1/20 1.00
STK39 Q9UEW8 5/20 0.72
PARG Q86W56 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rafoxanide SCHEMBL29422184 1.00 PNLIP (1.00) PNLIPMEN1HSPD1PIK3CAHTT
SCHEMBL20413308 0.91 PNLIP (0.84) PNLIPMEN1HSPD1PIK3CAHTT
SCHEMBL21579434 0.91 PNLIP (0.84) PNLIPMEN1HSPD1PIK3CAHTT
SCHEMBL21579433 0.91 PNLIP (0.84) PNLIPMEN1HSPD1PIK3CAHTT
SCHEMBL20844337 0.91 PNLIP (0.84) PNLIPMEN1HSPD1PIK3CAHTT
SCHEMBL22475377 0.89 PNLIP (0.80) PNLIPMEN1HSPD1PIK3CAHTT
SCHEMBL23685897 0.89 PNLIP (0.80) PNLIPMEN1HSPD1PIK3CAHTT
Rafoxanide SCHEMBL5310526 0.89 PNLIP (0.79) PNLIPMEN1HSPD1PIK3CAHTT
Rafoxanide SCHEMBL22362599 0.87 PNLIP (0.75) PNLIPMEN1HSPD1PIK3CAHTT
SCHEMBL14195174 0.83 KMT2A (0.70) PNLIPMEN1HSPD1PIK3CAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6554 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
US-20260091043-A1 COMPOSITIONS AND METHODS FOR TREATING MYCOBACTERIUM INFECTIONS DATA2DISCOVERY INC (US) 2026-04-02 US claimed
WO-2025244856-A1 METHODS AND COMPOSITIONS RELATING TO ELQ COMPOUNDS OREGON HEALTH & SCIENCE UNIVERSITY (US) 2025-11-27 WO claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
US-12471599-B2 Agricultural compositions comprising remodeled nitrogen fixing microbes PIVOT BIO, INC. (US) 2025-11-18 US claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
EP-4627920-A1 BINARY INSECTICIDE COMPOSITION AND USE THEREOF Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) 2025-10-08 EP claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
EP-4586826-A1 FEED AND METHODS FOR CONTROLLING HEARTWORM INFECTIONS IN A MAMMAL In the Bowl Animal Health, Inc. (US) 2025-07-23 EP claimed
US-20250185667-A1 AGRICULTURAL COMPOSITIONS COMPRISING REMODELED NITROGEN FIXING MICROBES HSBC BANK USA, N.A. 2025-06-12 US claimed
EP-0137627-A2 Pour-on formulation for the control of parasites PITMAN-MOORE AUSTRALIA LIMITED (AU) 1985-04-17 EP claimed
EP-0136033-A2 Pour-on formulation for the control of parasites ICI AUSTRALIA LIMITED (AU) 1985-04-03 EP claimed
EP-0059074-B1 ANTHELMINTIC COMPOSITION AND THE USE THEREOF SANKYO COMPANY LIMITED (JP) 1984-10-10 EP claimed
US-4468390-A Anthelmintic composition and the use thereof SANKYO COMPANY, LIMITED (JP) 1984-08-28 US claimed
EP-0059074-A1 Anthelmintic composition and the use thereof SANKYO COMPANY LIMITED (JP) 1982-09-01 EP claimed
EP-0003682-B1 PROCESS FOR SOLUBILIZING AN INSOLUBLE DRUG AND AN AQUEOUS SOLUTION PREPARED BY THIS PROCESS MERCK & CO. INC. (US) 1982-04-28 EP claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed
EP-0003682-A1 Process for solubilizing an insoluble drug and an aqueous solution prepared by this process MERCK & CO. INC. (US) 1979-08-22 EP claimed
US-4128632-A Solubilization of Rafoxanide MERCK & CO., INC. (US) 1978-12-05 US claimed
US-3956488-A ANTHELMINTICS MERCK & CO., INC. (US) 1976-05-11 US claimed