Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNLIP | P16233 | 14/20 | 0.84 |
| ▸ | MEN1 | O00255 | 1/20 | 0.84 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.84 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.84 |
| ▸ | HTT | P42858 | 1/20 | 0.84 |
| ▸ | BLM | P54132 | 1/20 | 0.84 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.84 |
| ▸ | STK39 | Q9UEW8 | 4/20 | 0.59 |
| ▸ | PARG | Q86W56 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rafoxanide SCHEMBL29422184 | 0.91 | PNLIP (1.00) | PNLIPMEN1HSPD1PIK3CAHTT | |
| Rafoxanide SCHEMBL118031 | 0.91 | PNLIP (1.00) | PNLIPMEN1HSPD1PIK3CAHTT | |
| SCHEMBL14195174 | 0.83 | KMT2A (0.70) | PNLIPMEN1HSPD1PIK3CAHTT | |
| SCHEMBL23685797 | 0.83 | PNLIP (0.70) | PNLIPMEN1HSPD1PIK3CAHTT | |
| SCHEMBL21579434 | 0.83 | PNLIP (0.84) | PNLIPMEN1HSPD1PIK3CAHTT | |
| SCHEMBL20413308 | 0.83 | PNLIP (0.84) | PNLIPMEN1HSPD1PIK3CAHTT | |
| SCHEMBL21579433 | 0.82 | PNLIP (0.84) | PNLIPMEN1HSPD1PIK3CAHTT | |
| Rafoxanide SCHEMBL5310526 | 0.81 | PNLIP (0.79) | PNLIPMEN1HSPD1PIK3CAHTT | |
| SCHEMBL22475377 | 0.81 | PNLIP (0.80) | PNLIPMEN1HSPD1PIK3CAHTT | |
| SCHEMBL23685897 | 0.81 | PNLIP (0.80) | PNLIPMEN1HSPD1PIK3CAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019058268-A1 | TOPICAL ANTI-INFECTIVE FORMULATION | Omnipharm Developments Limited (IE) | 2019-03-28 | — | — | WO | disclosed |