Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | AQP1 | P29972 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aniline SCHEMBL11809275 | 0.87 | CA2 (0.44) | CA2HSD17B10TSHRKDM4EUSP2 | |
| Acetanilide SCHEMBL11802093 | 0.87 | CISD1 (0.47) | CA2HSD17B10TSHRKDM4EUSP2 | |
| Acetanilide SCHEMBL11804849 | 0.86 | CA2 (0.42) | CA2HSD17B10TSHRKDM4EUSP2 | |
| Acetanilide SCHEMBL11799186 | 0.85 | CA2 (0.41) | CA2HSD17B10TSHRKDM4EUSP2 | |
| Acetanilide SCHEMBL11797057 | 0.84 | CA2 (0.41) | CA2HSD17B10TSHRKDM4EUSP2 | |
| Acetanilide SCHEMBL11798856 | 0.83 | PPARG (0.41) | CA2HSD17B10TSHRKDM4EUSP2 | |
| SCHEMBL11803709 | 0.81 | CA2 (0.39) | CA2HSD17B10TSHRKDM4EUSP2 | |
| Acetanilide SCHEMBL11800573 | 0.80 | HSD17B10 (0.46) | CA2HSD17B10KDM4EALDH1A1HPGD | |
| Acetanilide SCHEMBL11833341 | 0.77 | NAPRT (0.50) | CA2HSD17B10ALDH1A1NAPRTCA12 | |
| Acetanilide SCHEMBL11800242 | 0.76 | L3MBTL1 (0.48) | CA2HSD17B10TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3992440-A | DIURETICS | CIBA-GEIGY CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |
| US-3982018-A | DIURETICS | CIBA-GEIGY CORPORATION (US) | 1976-09-21 | — | — | US | disclosed |