Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11803544 | 0.82 | POLB (0.60) | LMNASMN1; SMN2CYP3A4MEN1CYP2C9 | |
| Hydrochloric Acid SCHEMBL11809846 | 0.77 | KDM4E (0.57) | MAPK1LMNASMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL28165285 | 0.76 | MAPK1 (0.55) | MAPK1LMNASMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL30543763 | 0.74 | NQO1 (0.48) | LMNASMN1; SMN2CYP3A4MEN1CYP1A2 | |
| SCHEMBL6242217 | 0.72 | KDM4E (0.55) | LMNASMN1; SMN2MEN1ADRA2AADORA3 | |
| SCHEMBL20570946 | 0.72 | ALDH1A1 (0.52) | LMNASMN1; SMN2MEN1CYP1A2KMT2A | |
| SCHEMBL11804167 | 0.71 | IDH1 (0.58) | CYP1A2CYP2C9KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11803024 | 0.70 | POLB (0.59) | CYP1A2CYP2C9KMT2AKDM4EALDH1A1 | |
| SCHEMBL20570106 | 0.70 | APP (0.50) | LMNAMEN1CYP1A2KMT2AKCNH2 | |
| SCHEMBL17423277 | 0.70 | KDM4E (0.59) | LMNACYP3A4MEN1CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3936457-A | VASODILATION | WARNER-LAMBERT COMPANY (US) | 1976-02-03 | — | — | US | claimed |
| US-3936457-A | VASODILATION | WARNER-LAMBERT COMPANY (US) | 1976-02-03 | — | — | US | disclosed |