Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.49 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242217 | 0.86 | KDM4E (0.55) | ALDH1A1KDM4EGAAHPGDTLR8 | |
| SCHEMBL17996024 | 0.84 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL982996 | 0.84 | P2RX4 (0.43) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL30543763 | 0.81 | NQO1 (0.48) | ALDH1A1KDM4EGAAHPGDTLR8 | |
| Hydrochloric Acid SCHEMBL11804926 | 0.80 | MAPT (0.54) | ALDH1A1KDM4EGAAHPGDTLR8 | |
| SCHEMBL17423277 | 0.80 | KDM4E (0.59) | ALDH1A1KDM4EGAAHPGDTLR8 | |
| SCHEMBL14130585 | 0.80 | KDM4E (0.61) | ALDH1A1KDM4EGAAHPGDKDM1A | |
| SCHEMBL13181729 | 0.79 | LMNA (0.45) | ALDH1A1KDM4EGAAHPGDTLR8 | |
| SCHEMBL8866398 | 0.79 | CYP1A2 (0.48) | ALDH1A1HPGDKMT2AMEN1CYP1A2 | |
| SCHEMBL17423228 | 0.79 | KDM4E (0.48) | ALDH1A1KDM4EGAAHPGDTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018217538-A1 | SYNTHESIS OF SUBSTITUTED ACRIDINES | UNIVERSITY OF ST. THOMAS (US) | 2018-11-29 | — | — | WO | disclosed |