Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 10/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11799473 | 0.80 | MAPT (0.43) | NPC1RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL7011056 | 0.80 | NPC1 (0.67) | S1PR4NPC1RAB9AMAPTLMNA | |
| SCHEMBL10779236 | 0.79 | ALDH1A1 (0.58) | S1PR4NPC1RAB9AMAPTLMNA | |
| SCHEMBL26647353 | 0.79 | NPC1 (0.40) | S1PR4NPC1RAB9AMAPTLMNA | |
| SCHEMBL5582814 | 0.79 | NPC1 (0.43) | S1PR4NPC1RAB9AMAPTLMNA | |
| SCHEMBL5582989 | 0.79 | S1PR4 (0.41) | S1PR4NPC1RAB9AMAPTLMNA | |
| SCHEMBL11835695 | 0.76 | MAPT (0.53) | NPC1RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL26646867 | 0.76 | TSHR (0.47) | NPC1RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL10702301 | 0.75 | MAPT (0.51) | NPC1RAB9AMAPTLMNAALDH1A1 | |
| SCHEMBL9694476 | 0.74 | GRIN2D (0.46) | MAPTLMNAHPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3974166-A | FUNGICIDE | CIBA-GEIGY CORPORATION (US) | 1976-08-10 | — | — | US | disclosed |