Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57727 | 1.00 | AKR1C4 (0.38) | AKR1C4AKR1C3AKR1C2METAP2ALOX15 | |
| SCHEMBL10385820 | 0.76 | AKR1C4 (0.40) | AKR1C4AKR1C3AKR1C2METAP2 | |
| SCHEMBL7604302 | 0.76 | PRKCA (0.36) | — | |
| SCHEMBL27922826 | 0.75 | ALOX15 (0.30) | ALOX15 | |
| SCHEMBL896555 | 0.73 | AKR1C4 (0.45) | AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL1931831 | 0.73 | AKR1C4 (0.45) | AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL2477329 | 0.73 | ALOX15 (0.31) | ALOX15 | |
| SCHEMBL10712782 | 0.69 | AKR1C4 (0.30) | AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL10713706 | 0.69 | AKR1C4 (0.30) | AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL10919799 | 0.69 | ALOX15 (0.31) | AKR1C4AKR1C3AKR1C2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941828-A | Process for the preparation of cyclic ketones | FIRMENICH SA (CH) | 1976-03-02 | — | — | US | disclosed |