Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.56 |
| ▸ | MTOR | P42345 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11810811 | 0.98 | ADRB2 (0.57) | ADRB2TSHRMAPTADRB1KDM4E | |
| Oxalic Acid SCHEMBL11816918 | 0.93 | MAPT (0.52) | ADRB2TSHRMAPTADRB1KDM4E | |
| Lactic Acid SCHEMBL11809840 | 0.92 | MAPT (0.54) | ADRB2TSHRMAPTADRB1KDM4E | |
| Hydrochloric Acid SCHEMBL11806256 | 0.87 | ADRB2 (0.44) | ADRB2TSHRMAPTADRB1KDM4E | |
| SCHEMBL11809441 | 0.87 | ADRB2 (0.42) | ADRB2TSHRMAPTADRB1KDM4E | |
| Hydrochloric Acid SCHEMBL11810810 | 0.86 | ADRB2 (0.43) | ADRB2TSHRMAPTADRB1KDM4E | |
| SCHEMBL11807914 | 0.84 | ADRB2 (0.57) | ADRB2TSHRMAPTADRB1KDM4E | |
| SCHEMBL11804077 | 0.84 | ADRB2 (0.55) | ADRB2TSHRMAPTADRB1KDM4E | |
| Gluconic Acid SCHEMBL11806325 | 0.83 | MAPT (0.51) | ADRB2TSHRMAPTADRB1KDM4E | |
| Hydrochloric Acid SCHEMBL11812398 | 0.82 | ADRB2 (0.56) | ADRB2TSHRMAPTADRB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954871-A | ANTIARRHYTHMIA, VASODILATOR, HYPOTENSIVE | CONTINENTAL PHARMA (BE) | 1976-05-04 | — | — | US | claimed |
| US-11931366-B2 | Compositions and methods of use thereof for treatment of proteinopathies | WASHINGTON UNIVERSITY (US) | 2024-03-19 | — | — | US | disclosed |
| US-20210228591-A1 | COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATMENT OF PROTEINOPATHIES | WASHINGTON UNIVERSITY | 2021-07-29 | — | — | US | disclosed |
| WO-2019204764-A1 | COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATMENT OF PROTEINOPATHIES | WASHINGTON UNIVERSITY (US) | 2019-10-24 | — | — | WO | disclosed |
| US-3954871-A | ANTIARRHYTHMIA, VASODILATOR, HYPOTENSIVE | CONTINENTAL PHARMA (BE) | 1976-05-04 | — | — | US | disclosed |
| US-3954851-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11931366-B2 | Compositions and methods of use thereof for treatment of proteinopathies | SERPINA2, FABP1, TTR | ADRB2 4160/4885TSHR 4106/4885MAPT 142/4885 |
| US-20210228591-A1 | COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATMENT OF PROTEINOPATHIES | SERPINA2, FABP1, TTR | ADRB2 4160/4885TSHR 4106/4885MAPT 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.