Known targets — ChEMBL curated mechanism
SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A
The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | BLM | P54132 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL11809840 | 0.85 | MAPT (0.54) | MAPTKDM4ETDP1ADRB2TSHR | |
| Oxalic Acid SCHEMBL11816918 | 0.84 | MAPT (0.52) | MAPTKDM4ETDP1ADRB2TSHR | |
| SCHEMBL11805102 | 0.83 | ADRB2 (0.56) | MAPTKDM4ETDP1ADRB2TSHR | |
| Hydrochloric Acid SCHEMBL11810811 | 0.82 | ADRB2 (0.57) | MAPTKDM4ETDP1ADRB2TSHR | |
| SCHEMBL11806335 | 0.82 | TAS1R3 (0.35) | MAPTKDM4ETDP1ADRB2TSHR | |
| Hydrochloric Acid SCHEMBL11806256 | 0.72 | ADRB2 (0.44) | MAPTKDM4ETDP1ADRB2TSHR | |
| SCHEMBL11809441 | 0.72 | ADRB2 (0.42) | MAPTKDM4ETDP1ADRB2TSHR | |
| Hydrochloric Acid SCHEMBL11810810 | 0.71 | ADRB2 (0.43) | MAPTKDM4ETDP1ADRB2TSHR | |
| SCHEMBL11811349 | 0.71 | MAPT (0.54) | MAPTKDM4ETDP1ADRB2TSHR | |
| SCHEMBL11807914 | 0.69 | ADRB2 (0.57) | MAPTKDM4ETDP1ADRB2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954871-A | ANTIARRHYTHMIA, VASODILATOR, HYPOTENSIVE | CONTINENTAL PHARMA (BE) | 1976-05-04 | — | — | US | disclosed |