Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 8/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.37 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11812316 | 0.90 | KDM4E (0.47) | KDM4EMEN1ALDH1A1TP53CYP2C9 | |
| SCHEMBL11775457 | 0.89 | TTR (0.49) | KDM4EMEN1ALDH1A1TP53CYP2C9 | |
| SCHEMBL11771221 | 0.87 | TTR (0.54) | KDM4EMEN1ALDH1A1TP53CYP2C9 | |
| SCHEMBL11485965 | 0.87 | KDM4E (0.45) | KDM4EMEN1ALDH1A1TP53CYP2C9 | |
| SCHEMBL11772872 | 0.87 | LTB4R (0.49) | KDM4EMEN1ALDH1A1TP53CYP2C9 | |
| SCHEMBL11768944 | 0.86 | KDM4E (0.64) | KDM4EMEN1ALDH1A1TP53CYP2C9 | |
| SCHEMBL11768779 | 0.86 | KDM4E (0.52) | KDM4EMEN1ALDH1A1TP53CYP2C9 | |
| SCHEMBL11814861 | 0.86 | LTB4R (0.55) | KDM4EMEN1ALDH1A1TP53CYP2C9 | |
| SCHEMBL11808532 | 0.86 | LTB4R (0.53) | KDM4EMEN1ALDH1A1TP53CYP2C9 | |
| SCHEMBL11767418 | 0.85 | TTR (0.49) | KDM4EMEN1ALDH1A1TP53CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3951618-A | Method of use of, and compositions containing, disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-04-20 | — | — | US | disclosed |