Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7557762 | 0.84 | TSHR (0.57) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL6673564 | 0.83 | ALDH1A1 (0.59) | THRBTSHRALDH1A1HTTTDP1 | |
| SCHEMBL16209800 | 0.82 | THRB (0.56) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL15901831 | 0.81 | THRB (0.55) | THRBTSHRALDH1A1POLBAPEX1 | |
| Ethylene SCHEMBL19209994 | 0.81 | THRB (0.60) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL15348117 | 0.80 | THRB (0.58) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL1398528 | 0.80 | THRB (0.61) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL7673814 | 0.80 | THRB (0.61) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL36524 | 0.79 | THRB (1.00) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL16250302 | 0.78 | HSD17B10 (0.42) | THRBTSHRALDH1A1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3935342-A | POLYMERIZATION WITH AN UNSATURATED SILYL MONOMER | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-27 | — | — | US | disclosed |