SCHEMBL11806091

SCHEMBL11806091

[CH2]c1ccc([CH2])c2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.39
HSD17B10 Q99714 4/20 0.39
CYP2A6 P11509 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
TSHR P16473 1/20 0.39
CYP1A2 P05177 4/20 0.37
IDO1 P14902 1/20 0.37
GPR3 P46089 4/20 0.35
HPRT1 P00492 1/20 0.35
KDM4E B2RXH2 3/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
KMT2A Q03164 1/20 0.33
HIF1A Q16665 1/20 0.32
CYP1B1 Q16678 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3953219 0.83 HPRT1 (0.37) ALDH1A1TSHRHPRT1KDM4EGAA
SCHEMBL2648160 0.83 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1TSHRIDO1
SCHEMBL7837636 0.83
SCHEMBL7837650 0.83 IDO1 (0.68) HSD17B10TDP1TSHRCYP1A2IDO1
SCHEMBL2860159 0.83 CYP1A2 (0.68) ALDH1A1HSD17B10CYP2A6TDP1TSHR
SCHEMBL3946391 0.83 RXFP1 (0.39) ALDH1A1CYP1A2KDM4ESMN1; SMN2MEN1
SCHEMBL5437391 0.83 CYP2A6 (0.68) ALDH1A1HSD17B10CYP2A6TDP1TSHR
SCHEMBL6312117 0.81 PARP1 (0.39) ALDH1A1HSD17B10CYP2A6KDM4EMAPK1
SCHEMBL7833168 0.79 GABRA1 (0.39) TSHRCYP1A2HIF1AHPGD
SCHEMBL7212039 0.77 CHEK1 (0.57) ALDH1A1TDP1TSHRCYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3947511-A RUBBER CURING AGENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-03-30 US disclosed