Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11858474 | 0.87 | CYP1A2 (0.34) | LMNAHTTALDH1A1TDP1TSHR | |
| SCHEMBL11861925 | 0.86 | LMNA (0.39) | LMNAHTTSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL11825070 | 0.85 | ALDH1A1 (0.37) | ALDH1A1TDP1TSHRCYP1A2CYP3A4 | |
| SCHEMBL11810808 | 0.85 | LMNA (0.39) | LMNAHTTSMN1; SMN2ALDH1A1DCTPP1 | |
| SCHEMBL11813301 | 0.83 | LMNA (0.37) | LMNAHTTSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL11861299 | 0.81 | ALDH1A1 (0.37) | LMNASMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL11806507 | 0.81 | TDP1 (0.40) | LMNAHTTSMN1; SMN2TDP1TSHR | |
| SCHEMBL11559410 | 0.81 | TDP1 (0.36) | LMNAHTTSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL11804831 | 0.79 | TDP1 (0.39) | LMNAHTTSMN1; SMN2TDP1TSHR | |
| SCHEMBL11855183 | 0.77 | ALDH1A1 (0.36) | LMNASMN1; SMN2ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954788-A | INTERMEDIATES FOR HERBIDIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |
| US-3954438-A | 5-Trifluoromethyl-7-aminobenzimidazoles herbicides | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |