Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.60 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | MC3R | P41968 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11807287 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL11875844 | 0.91 | ALDH1A1 (0.59) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL11808076 | 0.85 | POLB (0.46) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL11805973 | 0.85 | POLB (0.46) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL11808967 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL11808624 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL25118509 | 0.82 | KDM4E (0.52) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL11623420 | 0.81 | KDM4E (0.51) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL11725999 | 0.81 | KDM4E (0.52) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL11726005 | 0.81 | KDM4E (0.52) | ALDH1A1KDM4EHKDC1TDP1SAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931282-A | 11α-Hydroxymethyl prostaglandins | SYNTEX (U.S.A.) INC. (US) | 1976-01-06 | — | — | US | disclosed |