Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6358868 | 0.98 | NPSR1 (0.42) | NPSR1RAB9AALDH1A1POLBMAPT | |
| SCHEMBL11806820 | 0.90 | NPSR1 (0.35) | NPSR1RAB9AALDH1A1POLBMAPT | |
| SCHEMBL2957126 | 0.78 | NPSR1 (0.45) | NPSR1RAB9AALDH1A1POLBMAPT | |
| SCHEMBL1544893 | 0.76 | ALDH1A1 (0.46) | ALDH1A1POLBMAPTHPGD | |
| SCHEMBL11721146 | 0.74 | ATM (0.37) | ATM | |
| SCHEMBL19281550 | 0.72 | HSD11B1 (0.33) | ALDH1A1HPGD | |
| SCHEMBL19520381 | 0.71 | SMN1; SMN2 (0.50) | NPSR1ALDH1A1POLBHPGD | |
| SCHEMBL20816364 | 0.69 | NPSR1 (0.39) | NPSR1RAB9AALDH1A1POLBMAPT | |
| SCHEMBL390783 | 0.69 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDHSD17B10L3MBTL1 | |
| SCHEMBL5334498 | 0.68 | ALDH1A1 (0.45) | NPSR1RAB9AALDH1A1HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954984-A | ANTISECRETRETORY AGENTS, CENTRAL NERVOUS SYSTEM DEPRESSANTS | RICHARDSON-MERRELL INC. (US) | 1976-05-04 | — | — | US | disclosed |
| US-3954981-A | Triazolocycloalkylhydrothiadiazine derivatives | RICHARDSON-MERRELL INC. (US) | 1976-05-04 | — | — | US | disclosed |