Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11807258 | 0.94 | LMNA (0.38) | ADRA2AADRA1AMAPTBLMTSHR | |
| SCHEMBL11202989 | 0.93 | DGKA (0.42) | ADRA2AADRA1AMAPTBLMTSHR | |
| SCHEMBL4259488 | 0.92 | DGKA (0.44) | TSHRNFKB1CYP2C19DGKA | |
| SCHEMBL11806697 | 0.89 | TSHR (0.37) | TSHRNFKB1CYP2C19LMNATP53 | |
| SCHEMBL11809257 | 0.88 | DGKA (0.38) | TSHRNFKB1CYP2C19DGKALMNA | |
| SCHEMBL11810335 | 0.86 | DGKA (0.40) | TSHRNFKB1CYP2C19DGKALMNA | |
| SCHEMBL11154148 | 0.86 | DGKA (0.56) | MAPTTSHRDGKALMNA | |
| SCHEMBL11813600 | 0.86 | DGKA (0.56) | MAPTTSHRDGKALMNA | |
| SCHEMBL11807662 | 0.85 | TSHR (0.39) | TSHRNFKB1CYP2C19LMNATP53 | |
| SCHEMBL11806693 | 0.85 | TSHR (0.38) | TSHRNFKB1CYP2C19LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975357-A | SUBSTITUTED PIPERIDINES | SANKYO COMPANY LIMITED (JA) | 1976-08-17 | — | — | US | claimed |
| US-3975357-A | SUBSTITUTED PIPERIDINES | SANKYO COMPANY LIMITED (JA) | 1976-08-17 | — | — | US | disclosed |