Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.39 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20099509 | 0.88 | ALDH1A1 (0.47) | ALDH1A1KDM4EPOLBRAB9ANPC1 | |
| SCHEMBL11805756 | 0.86 | ALDH1A1 (0.61) | ALDH1A1KDM4ECYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11835382 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KDM4ECYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11859092 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KDM4ECYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11863454 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KDM4ECYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8558621 | 0.81 | KDM4E (0.67) | ALDH1A1KDM4EPOLBRAB9ANPC1 | |
| SCHEMBL30999865 | 0.79 | MAOA (0.60) | ALDH1A1KDM4ECYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3091546 | 0.79 | MAOA (0.60) | ALDH1A1KDM4ECYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11812047 | 0.79 | KDM4E (0.56) | ALDH1A1KDM4ERAB9ANPC1KMT2A | |
| SCHEMBL11810960 | 0.79 | KDM4E (0.52) | ALDH1A1KDM4ERAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240343738-A1 | Method for preparing pranoprofen and composition comprising pranoprofen and impurity | SHENYANG XINGQI PHARMACEUTICAL CO., LTD. (CN) | 2024-10-17 | — | — | US | disclosed |
| EP-4361155-A1 | METHOD FOR PREPARING PRANOPROFEN AND COMPOSITION CONTAINING PRANOPROFEN AND IMPURITY | Shenyang Xingqi Pharmaceutical Co., Ltd. (CN) | 2024-05-01 | — | — | EP | disclosed |
| CN-115677733-A | Compound for pranoprofen quality research and preparation method and application thereof | 济南宣正药业有限公司 | 2023-02-03 | — | — | CN | disclosed |
| WO-2022267945-A1 | METHOD FOR PREPARING PRANOPROFEN AND COMPOSITION CONTAINING PRANOPROFEN AND IMPURITY | 沈阳兴齐眼药股份有限公司 | 2022-12-29 | — | — | WO | disclosed |
| US-3931199-A | ANTIALLERGY | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240343738-A1 | Method for preparing pranoprofen and composition comprising pranoprofen and impurity | CYP3A5, CYP3A43, CYP4A11 | ALDH1A1 205/4885KDM4E 3123/4885CYP19A1 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.