Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 2/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 2/20 | 0.36 |
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzimidazole SCHEMBL28656219 | 0.89 | PARP1 (0.36) | KDM4EALDH1A1SMN1; SMN2RAB9AHPGD | |
| Benzimidazole SCHEMBL28306492 | 0.82 | SMN1; SMN2 (0.48) | KDM4EALDH1A1SMN1; SMN2RAB9AHPGD | |
| Benzimidazole SCHEMBL28467045 | 0.80 | SMN1; SMN2 (0.47) | KDM4EALDH1A1SMN1; SMN2RAB9AHPGD | |
| Benzimidazole SCHEMBL28472447 | 0.80 | SMN1; SMN2 (0.47) | KDM4EALDH1A1SMN1; SMN2RAB9AHPGD | |
| Benzimidazole SCHEMBL4894704 | 0.80 | SMN1; SMN2 (0.47) | KDM4EALDH1A1SMN1; SMN2RAB9AHPGD | |
| Benzimidazole SCHEMBL28471263 | 0.80 | SMN1; SMN2 (0.47) | KDM4EALDH1A1SMN1; SMN2RAB9AHPGD | |
| Benzimidazole SCHEMBL5133620 | 0.80 | SMN1; SMN2 (0.47) | KDM4EALDH1A1SMN1; SMN2RAB9AHPGD | |
| Benzimidazole SCHEMBL461969 | 0.80 | SMN1; SMN2 (0.50) | KDM4EALDH1A1SMN1; SMN2RAB9AHPGD | |
| Benzimidazole SCHEMBL10931770 | 0.80 | SMN1; SMN2 (0.50) | KDM4EALDH1A1SMN1; SMN2RAB9AHPGD | |
| Benzimidazole SCHEMBL6009 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111417610-A | Ceramic-polymer composite material obtained by cold sintering process | 沙特基础工业全球技术有限公司 | 2020-07-14 | — | — | CN | claimed |
| CN-116517952-A | Sliding bearing with high polymer coating and preparation method thereof | 浙江长盛滑动轴承股份有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116354889-A | Process for preparing benzimidazole derivatives | 怡诺安有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-113167323-B | Plain bearing, in particular for a gear of a wind power plant | 米巴滑动轴承奥地利有限公司 | 2023-03-24 | — | — | CN | disclosed |
| US-11318229-B2 | Method for producing an implant using a calcium carbonate-containing composite powder comprising microstructured particles | KARL LEIBINGER MEDIZINTECHNIK GMBH & CO. KG (DE) | 2022-05-03 | — | — | US | disclosed |
| US-11124654-B2 | Method for producing an implant comprising calcium carbonate-containing composite powder having microstructured particles having inhibiting calcium carbonate | KARL LEIBINGER MEDIZINTECHNIK GMBH & CO. KG (DE) | 2021-09-21 | — | — | US | disclosed |
| CN-112912456-A | Adhesive tape | 日东电工株式会社 | 2021-06-04 | — | — | CN | disclosed |
| US-20190351104-A1 | IMPLANT THAT CONTAINS INHIBITING CALCIUM CARBONATE | KARL LEIBINGER MEDIZINTECHNIK GMBH & CO. KG (DE) | 2019-11-21 | — | — | US | disclosed |
| US-20190216980-A1 | METHOD FOR PRODUCING AN IMPLANT USING A CALCIUM CARBONATE-CONTAINING COMPOSITE POWDER COMPRISING MICROSTRUCTURED PARTICLES | KARL LEIBINGER ASSET MANAGEMENT GMBH & CO. KG (DE) | 2019-07-18 | — | — | US | disclosed |
| US-20190194468-A1 | Method for producing an implant comprising calcium carbonate-containing composite powder having microstructured particles having inhibiting calcium carbonate | KARL LEIBINGER ASSET MANAGEMENT GMBH & CO. KG (DE) | 2019-06-27 | — | — | US | disclosed |
| CN-109789247-A | Contain the implantation material for inhibiting calcium carbonate | 卡尔莱布宁医疗技术有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-109661419-A | Inhibiting calcium carbonate additives | 谢菲尔考克有限两合公司 | 2019-04-19 | — | — | CN | disclosed |
| US-10183949-B2 | Pyrimidinone derivative having autotaxin-inhibitory activity | THE UNIVERSITY OF TOKYO (JP) | 2019-01-22 | — | — | US | disclosed |
| CN-109074918-A | insulated electrical conductor | 格鲍尔格里勒金属有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-104049014-B | With Mn2O3The sensor and its manufacture method of catalyst | 霍夫曼-拉罗奇有限公司 | 2018-04-27 | — | — | CN | disclosed |
| EP-3187492-A1 | PYRIMIDINONE DERIVATIVE HAVING AUTOTAXIN-INHIBITORY ACTIVITY | The University of Tokyo (JP) | 2017-07-05 | — | — | EP | disclosed |
| US-20170158704-A1 | PYRIMIDINONE DERIVATIVE HAVING AUTOTAXIN-INHIBITORY ACTIVITY | THE UNIVERSITY OF TOKYO (JP) | 2017-06-08 | — | — | US | disclosed |
| US-3951920-A | Permselective polymeric membrane prepared from polybenzimidazoles | TEIJIN LIMITED (JA) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158704-A1 | PYRIMIDINONE DERIVATIVE HAVING AUTOTAXIN-INHIBITORY ACTIVITY | ENPP2, ITPA, IMPA1 | KDM4E 3026/4885ALDH1A1 3520/4885SMN1; SMN2 3666/4885 |
| US-10183949-B2 | Pyrimidinone derivative having autotaxin-inhibitory activity | ENPP2, ITPA, IMPA1 | KDM4E 3026/4885ALDH1A1 3520/4885SMN1; SMN2 3666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.