Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.63 |
| ▸ | PARP11 | Q9NR21 | 5/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.46 |
| ▸ | PARP1 | P09874 | 4/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.38 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3051114 | 0.81 | CDC7 (0.47) | CDC7PARP1PLA2G2APLA2G4AGRM5 | |
| SCHEMBL13145547 | 0.78 | CDC7 (0.49) | CDC7PARP1PLA2G2APLA2G4AHPGD | |
| SCHEMBL10824405 | 0.70 | PLA2G2A (0.50) | PARP1PLA2G2APLA2G4AHPGDSMN1; SMN2 | |
| SCHEMBL25292799 | 0.70 | PARP11 (0.82) | PARP11PARP10PARP1PDPK1TYRO3 | |
| SCHEMBL11813154 | 0.70 | HTR6 (0.40) | CDK5CDK5R1PLA2G2APLA2G4AHPGD | |
| SCHEMBL10427272 | 0.70 | CDC7 (0.41) | CDC7PARP1PLA2G2APLA2G4AHPGD | |
| SCHEMBL12546313 | 0.69 | PARP10 (0.81) | PARP11PARP10PARP1PDPK1CDK5 | |
| SCHEMBL22905580 | 0.69 | CDC7 (0.40) | CDC7PARP11PARP10PARP1CDK5 | |
| Hydrochloric Acid SCHEMBL11812473 | 0.69 | HTR6 (0.40) | PLA2G2APLA2G4AHPGDNPC1CYP3A4 | |
| SCHEMBL28588903 | 0.67 | NPC1 (0.40) | PARP1PLA2G2APLA2G4AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3952025-A | ANALGESIC, TRANQUILIZER | AMERICAN HOECHST CORPORATION (US) | 1976-04-20 | — | — | US | disclosed |