Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | ESR1 | P03372 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10869267 | 0.84 | ALDH1A1 (0.64) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL1698927 | 0.82 | ALDH1A1 (0.45) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL31302993 | 0.80 | ALOX15 (0.43) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL15941838 | 0.80 | ALDH1A1 (0.57) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL1501111 | 0.80 | ALDH1A1 (0.73) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL29358687 | 0.80 | ALDH1A1 (1.00) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL50705 | 0.80 | ALDH1A1 (1.00) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL29328732 | 0.79 | TDP1 (0.57) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL28166013 | 0.79 | ALDH1A1 (0.57) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL23861435 | 0.78 | ALDH1A1 (0.70) | ALDH1A1ALOX15HPGDHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3987200-A | INOTROPIC AGENTS, 3,4-DIHYDROXY-PHENYL-ALKYL PHENETHYLAMINE | ELI LILLY AND COMPANY (US) | 1976-10-19 | — | — | US | disclosed |