Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 8/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TBK1 | Q9UHD2 | 5/20 | 0.51 |
| ▸ | IKBKE | Q14164 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11815286 | 0.83 | NPC1 (0.54) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11815861 | 0.81 | NPC1 (0.59) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10883360 | 0.81 | NPC1 (0.84) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11811214 | 0.78 | NPC1 (0.66) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11809988 | 0.78 | NPC1 (0.48) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11860618 | 0.77 | TBK1 (0.56) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10510862 | 0.76 | TBK1 (0.85) | NPC1RAB9AKDM4ETBK1IKBKE | |
| SCHEMBL11883817 | 0.75 | NPC1 (0.74) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10510866 | 0.74 | TBK1 (0.61) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10882826 | 0.74 | NPC1 (1.00) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931199-A | ANTIALLERGY | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JA) | 1976-01-06 | — | — | US | claimed |