Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11806966 | 0.90 | TLR7 (0.31) | — | |
| SCHEMBL11812366 | 0.84 | ADRB2 (0.30) | ADRB2ADRB1 | |
| SCHEMBL11517572 | 0.83 | KDM4E (0.40) | MEN1KMT2A | |
| SCHEMBL11865094 | 0.80 | ABL1 (0.37) | ABL1MEN1KMT2A | |
| SCHEMBL11810909 | 0.80 | GRM2 (0.35) | — | |
| SCHEMBL11814233 | 0.80 | XPO1 (0.30) | — | |
| SCHEMBL11810331 | 0.80 | S1PR1 (0.34) | ABL1 | |
| SCHEMBL11515409 | 0.77 | ABL1 (0.32) | ABL1 | |
| SCHEMBL11819659 | 0.75 | — | — | |
| SCHEMBL11815308 | 0.75 | CFTR (0.32) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954438-A | 5-Trifluoromethyl-7-aminobenzimidazoles herbicides | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |