Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11806966 | 0.90 | TLR7 (0.31) | DYRK1ATLR7 | |
| SCHEMBL11809266 | 0.80 | ABL1 (0.35) | — | |
| SCHEMBL11819659 | 0.80 | — | — | |
| SCHEMBL11812366 | 0.79 | ADRB2 (0.30) | — | |
| SCHEMBL11805651 | 0.79 | CDK9 (0.40) | DYRK1ACNR1CNR2 | |
| SCHEMBL11804036 | 0.78 | TLR8 (0.38) | DYRK1ACNR1CNR2POLB | |
| SCHEMBL11517572 | 0.78 | KDM4E (0.40) | DYRK1A | |
| SCHEMBL11810702 | 0.76 | CTSS (0.33) | — | |
| SCHEMBL11814233 | 0.75 | XPO1 (0.30) | — | |
| SCHEMBL11812486 | 0.75 | KMT2A (0.33) | DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954438-A | 5-Trifluoromethyl-7-aminobenzimidazoles herbicides | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |