Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11809684 | 0.89 | ALDH1A1 (0.49) | GRM5ALDH1A1ALDH2ALDH3A1KMT2A | |
| SCHEMBL11808207 | 0.88 | GRM5 (0.42) | GRM5ALDH1A1POLBKMT2AMITF | |
| SCHEMBL11828654 | 0.87 | ALDH1A1 (0.42) | CYP19A1GRM5ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL11809007 | 0.85 | CHRM5 (0.39) | ALDH1A1ALDH2ALDH3A1KMT2ANPSR1 | |
| SCHEMBL11819315 | 0.84 | NR1I2 (0.52) | CYP19A1ALDH1A1MAPTPOLBHTT | |
| SCHEMBL11812695 | 0.84 | CYP19A1 (0.48) | CYP19A1ALDH1A1MAPTPOLBPTGDR2 | |
| SCHEMBL11802980 | 0.84 | CYP19A1 (0.43) | CYP19A1GRM5ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL11859900 | 0.83 | MAPT (0.44) | CYP19A1GRM5ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL11812536 | 0.81 | CYP19A1 (0.38) | CYP19A1GRM5ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL11830109 | 0.79 | ALDH1A1 (0.41) | CYP19A1GRM5ALDH1A1ALDH2ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941803-A | 2-(Imidazol-1-yl)benzophenones | THE UPJOHN COMPANY (US) | 1976-03-02 | — | — | US | disclosed |