Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 6/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11808207 | 0.89 | GRM5 (0.42) | ALDH1A1MITFHSP90AA1HTTATM | |
| SCHEMBL11809388 | 0.89 | CYP19A1 (0.45) | ALDH1A1MITFHSP90AA1HTTATM | |
| SCHEMBL11813896 | 0.89 | NR1I2 (0.51) | ALDH1A1HTTGRM5ALDH2ALDH3A1 | |
| SCHEMBL11828654 | 0.88 | ALDH1A1 (0.42) | ALDH1A1HSP90AA1ATMNPSR1TLR9 | |
| SCHEMBL11806161 | 0.87 | GRM5 (0.42) | ALDH1A1GRM5ALDH2ALDH3A1NR1I2 | |
| SCHEMBL11809007 | 0.86 | CHRM5 (0.39) | ALDH1A1NPSR1ALDH2ALDH3A1KMT2A | |
| SCHEMBL11813256 | 0.86 | GRM5 (0.41) | ALDH1A1GRM5ALDH2ALDH3A1KMT2A | |
| SCHEMBL11819315 | 0.85 | NR1I2 (0.52) | ALDH1A1HTTNR1I2OPRK1CHRNA4 | |
| SCHEMBL11810208 | 0.85 | ALDH1A1 (0.52) | ALDH1A1MITFHSP90AA1HTTATM | |
| SCHEMBL11803706 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MITFHSP90AA1HTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941803-A | 2-(Imidazol-1-yl)benzophenones | THE UPJOHN COMPANY (US) | 1976-03-02 | — | — | US | claimed |
| US-3941803-A | 2-(Imidazol-1-yl)benzophenones | THE UPJOHN COMPANY (US) | 1976-03-02 | — | — | US | disclosed |