Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL117685 | 0.85 | ACE2 (0.44) | ACE2PPARGABCG2MAOBACHE | |
| SCHEMBL4150944 | 0.80 | MAOB (0.51) | ACE2PPARGABCG2MAOBACHE | |
| SCHEMBL4153233 | 0.80 | ABCG2 (0.63) | PPARGABCG2MAOBACHENPC1 | |
| SCHEMBL117674 | 0.80 | MAOB (0.50) | ACE2PPARGABCG2MAOBACHE | |
| SCHEMBL3718620 | 0.79 | ABCG2 (0.46) | ACE2PPARGABCG2MAOBACHE | |
| SCHEMBL4150940 | 0.79 | ABCG2 (0.48) | ACE2PPARGABCG2MAOBACHE | |
| SCHEMBL1421774 | 0.78 | ABCG2 (0.61) | PPARGABCG2MAOBACHENPC1 | |
| SCHEMBL3759824 | 0.78 | MAOB (0.46) | ACE2PPARGABCG2MAOBACHE | |
| SCHEMBL13056287 | 0.78 | ACE2 (0.47) | ACE2PPARGABCG2MAOBACHE | |
| SCHEMBL7548319 | 0.78 | MAOB (0.48) | ACE2ABCG2MAOBACHENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424541-A2 | PHOSPHORYLATED AND PHOSPHONATED PYRONE ANALOGS FOR THERAPEUTIC TREATMENT | Limerick BioPharma, Inc. (US) | 2012-03-07 | — | — | EP | disclosed |