Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1421774 | 0.92 | ABCG2 (0.61) | ABCG2KDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL4167435 | 0.91 | ABCG2 (0.70) | ABCG2KDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL4150940 | 0.88 | ABCG2 (0.48) | ABCG2KDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL1180724 | 0.88 | ABCG2 (0.51) | ABCG2KDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL4150944 | 0.88 | MAOB (0.51) | ABCG2MAPTMAOBACHEABCB1 | |
| SCHEMBL7548319 | 0.87 | MAOB (0.48) | ABCG2MAOBACHEABCB1TDP1 | |
| SCHEMBL3759824 | 0.85 | MAOB (0.46) | ABCG2KDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL4164670 | 0.85 | MAPT (0.60) | ABCG2KDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL7545480 | 0.85 | PPARG (0.70) | ABCG2KDM4EALDH1A1CYP3A4MEN1 | |
| SCHEMBL3718620 | 0.85 | ABCG2 (0.46) | ABCG2MAPTMAOBACHEABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) | 2009-05-21 | — | — | US | claimed |
| US-20020147353-A1 | Novel flavonoids | VERENIGING CHRISTELIJK WETENSCHAPPELIJK ANDERWIJS (NL) | 2002-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147353-A1 | Novel flavonoids | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1, ABCC8 | ABCG2 326/4885KDM4E 3228/4885ALDH1A1 1596/4885 |
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | CAT, NQO1, GPX4 | ABCG2 102/4885KDM4E 4144/4885ALDH1A1 609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.