Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 15/20 | 0.62 |
| ▸ | TP53 | P04637 | 9/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2985659 | 0.89 | LMNA (0.63) | LMNASMN1; SMN2MAPTTP53THRB | |
| SCHEMBL2997027 | 0.85 | MAPT (0.72) | LMNASMN1; SMN2MAPTTP53THRB | |
| SCHEMBL28537824 | 0.82 | MAPT (0.56) | LMNASMN1; SMN2MAPTTP53THRB | |
| SCHEMBL11814051 | 0.82 | LMNA (0.70) | LMNASMN1; SMN2MAPTTP53THRB | |
| SCHEMBL2994406 | 0.80 | SERPINE1 (0.70) | LMNASMN1; SMN2MAPTTP53THRB | |
| SCHEMBL11696697 | 0.80 | MAPT (0.57) | LMNASMN1; SMN2MAPTTP53THRB | |
| SCHEMBL11841289 | 0.79 | MAPT (0.58) | LMNASMN1; SMN2MAPTTP53THRB | |
| SCHEMBL2985685 | 0.79 | SERPINE1 (0.69) | LMNASMN1; SMN2MAPTTP53THRB | |
| SCHEMBL2997341 | 0.79 | MAPT (0.59) | LMNASMN1; SMN2MAPTTP53THRB | |
| SCHEMBL11834489 | 0.78 | SERPINE1 (0.57) | LMNASMN1; SMN2MAPTTP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3968121-A | 1,2-Diphenyl-4,5,6,7-tetrahydroindoles | STERLING DRUG INC. (US) | 1976-07-06 | — | — | US | claimed |
| US-3968121-A | 1,2-Diphenyl-4,5,6,7-tetrahydroindoles | STERLING DRUG INC. (US) | 1976-07-06 | — | — | US | disclosed |