Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 9/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2985659 | 0.86 | LMNA (0.63) | MAPTLMNATP53SMN1; SMN2THRB | |
| SCHEMBL11809804 | 0.82 | LMNA (0.67) | MAPTLMNATP53SMN1; SMN2THRB | |
| SCHEMBL11814051 | 0.79 | LMNA (0.70) | MAPTLMNATP53SMN1; SMN2THRB | |
| SCHEMBL2997027 | 0.79 | MAPT (0.72) | MAPTLMNATP53SMN1; SMN2THRB | |
| SCHEMBL11834489 | 0.75 | SERPINE1 (0.57) | MAPTLMNATP53SMN1; SMN2THRB | |
| SCHEMBL15283682 | 0.73 | MAPT (0.50) | MAPTLMNATP53SMN1; SMN2THRB | |
| SCHEMBL2997341 | 0.73 | MAPT (0.59) | MAPTLMNATP53SMN1; SMN2THRB | |
| SCHEMBL11816949 | 0.72 | LMNA (0.55) | MAPTLMNATP53SMN1; SMN2THRB | |
| SCHEMBL2994406 | 0.72 | SERPINE1 (0.70) | MAPTLMNATP53SMN1; SMN2THRB | |
| SCHEMBL11696697 | 0.72 | MAPT (0.57) | MAPTLMNATP53SMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107496419-B | Cyclopenta [ b ] pyrrole compound with anti-inflammatory activity | 兰州大学 | 2021-03-23 | — | — | CN | disclosed |