Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | CTSH | P09668 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.32 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27932216 | 0.79 | TSHR (0.39) | SMN1; SMN2LMNACHRM2CHRM4CHRM1 | |
| SCHEMBL11812907 | 0.79 | TSHR (0.39) | SMN1; SMN2LMNACHRM2CHRM4CHRM1 | |
| SCHEMBL11810557 | 0.77 | ALDH1A1 (0.40) | CTSKALDH1A1SMN1; SMN2LMNACHRM2 | |
| SCHEMBL11807399 | 0.74 | LMNA (0.33) | ALDH1A1SMN1; SMN2LMNATSHRNFKB1 | |
| SCHEMBL14325583 | 0.73 | SMN1; SMN2 (0.40) | CTSLCTSBCTSKCTSHALDH1A1 | |
| SCHEMBL2980853 | 0.73 | ALDH1A1 (0.42) | CTSLCTSBCTSKCTSHALDH1A1 | |
| SCHEMBL2987026 | 0.73 | ALDH1A1 (0.42) | CTSLCTSBCTSKCTSHALDH1A1 | |
| SCHEMBL2987876 | 0.73 | ALDH1A1 (0.42) | CTSLCTSBCTSKCTSHALDH1A1 | |
| SCHEMBL2240092 | 0.73 | ALDH1A1 (0.42) | CTSLCTSBCTSKCTSHALDH1A1 | |
| SCHEMBL2984192 | 0.73 | ALDH1A1 (0.42) | CTSLCTSBCTSKCTSHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975357-A | SUBSTITUTED PIPERIDINES | SANKYO COMPANY LIMITED (JA) | 1976-08-17 | — | — | US | disclosed |