SCHEMBL11810596

SCHEMBL11810596

C=C(Cl)C(=O)OCCO[Si](C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.37
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL679847 0.82 THRB (0.57) THRBTSHR
Ethylene SCHEMBL4924510 0.80 THRB (0.41) THRBTSHR
SCHEMBL11809058 0.80 THRB (0.37) THRBTSHR
SCHEMBL11803402 0.80 THRB (0.37) THRBTSHR
SCHEMBL11806965 0.77 THRB (0.61) THRBTSHR
SCHEMBL11806859 0.77 THRB (0.61) THRBTSHR
SCHEMBL11805482 0.77 THRB (0.61) THRBTSHR
SCHEMBL11043312 0.77 ALDH1A1 (0.46) THRBTSHR
SCHEMBL1470702 0.76 THRB (0.48) THRBTSHR
SCHEMBL8962437 0.76 THRB (0.33) THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3935342-A POLYMERIZATION WITH AN UNSATURATED SILYL MONOMER MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-01-27 US disclosed