Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741920 | 0.89 | HRH1 (0.55) | KMT2ALMNASMN1; SMN2NPSR1POLB | |
| SCHEMBL9913696 | 0.78 | MEN1 (0.76) | KMT2AMEN1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL11145527 | 0.78 | LMNA (0.65) | KMT2AMEN1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL11452149 | 0.78 | GAA (0.66) | KMT2AMEN1LMNANPSR1POLB | |
| SCHEMBL7625308 | 0.77 | LMNA (0.68) | KMT2AMEN1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL8611070 | 0.76 | MEN1 (0.79) | KMT2AMEN1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL9913722 | 0.75 | KMT2A (0.55) | KMT2AMEN1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL11564141 | 0.74 | MAPK1 (0.54) | KMT2AMEN1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL13784260 | 0.72 | MEN1 (0.68) | KMT2AMEN1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL13208246 | 0.71 | GAA (0.58) | KMT2AMEN1LMNANPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3988292-A | A TRIAZINE DERIVATIVE | TEIJIN LIMITED (JA) | 1976-10-26 | — | — | US | disclosed |