Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 6/20 | 0.39 |
| ▸ | TTR | P02766 | 5/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR1D | P28221 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.32 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11813838 | 0.87 | TTR (0.39) | LTB4RTTRHTR1AHTR1DHTR2C | |
| SCHEMBL11768520 | 0.80 | TTR (0.50) | LTB4RTTRNPC1RAB9ALTB4R2 | |
| SCHEMBL11808742 | 0.78 | TTR (0.40) | LTB4RTTRHTR1AHTR1DHTR2C | |
| SCHEMBL11767062 | 0.78 | NPC1 (0.37) | LTB4RTTRHTR1AHTR1DHTR2C | |
| SCHEMBL11772658 | 0.78 | TTR (0.50) | LTB4RTTRNPC1RAB9ALTB4R2 | |
| SCHEMBL11766679 | 0.74 | LTB4R (0.50) | LTB4RTTRNPC1RAB9ALTB4R2 | |
| SCHEMBL11770751 | 0.73 | TTR (0.53) | LTB4RTTRNPC1RAB9ALTB4R2 | |
| SCHEMBL11772891 | 0.73 | TTR (0.53) | LTB4RTTRNPC1RAB9ALTB4R2 | |
| SCHEMBL11774586 | 0.73 | LTB4R (0.52) | LTB4RTTRLTB4R2CYP2C9HSD17B10 | |
| SCHEMBL11771303 | 0.73 | TTR (0.52) | LTB4RTTRNPC1RAB9ALTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3951618-A | Method of use of, and compositions containing, disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-04-20 | — | — | US | disclosed |