Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 5/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.33 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11772658 | 0.90 | TTR (0.50) | TTRLTB4RNPC1RAB9AAKR1B1 | |
| SCHEMBL11808742 | 0.89 | TTR (0.40) | TTRLTB4RNPC1RAB9AHTR1A | |
| SCHEMBL11812781 | 0.87 | LTB4R (0.39) | TTRLTB4RNPC1RAB9AHTR1A | |
| SCHEMBL11771365 | 0.84 | LTB4R (0.50) | TTRLTB4RNPC1RAB9AAKR1B1 | |
| SCHEMBL11770946 | 0.83 | LTB4R (0.52) | TTRLTB4RAKR1B1ALDH1A1HPGD | |
| SCHEMBL11813660 | 0.81 | NPC1 (0.41) | TTRNPC1RAB9AHTR1AHTR1D | |
| SCHEMBL11771326 | 0.79 | TTR (0.52) | TTRLTB4RNPC1RAB9AAKR1B1 | |
| SCHEMBL11808417 | 0.78 | NPC1 (0.39) | TTRLTB4RNPC1RAB9AHTR1A | |
| SCHEMBL11816756 | 0.77 | LTB4R (0.52) | TTRLTB4RALDH1A1HPGDKDM4E | |
| Potassium Ion SCHEMBL11811806 | 0.77 | NPC1 (0.41) | TTRLTB4RNPC1RAB9AAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3951618-A | Method of use of, and compositions containing, disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-04-20 | — | — | US | disclosed |