Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL971070 | 0.78 | — | — | |
| SCHEMBL15269810 | 0.74 | KDM4E (0.31) | ALDH1A1KDM4EHMGCRCHRM1TBXA2R | |
| SCHEMBL10437649 | 0.74 | KDM4E (0.31) | ALDH1A1KDM4EHMGCRCHRM1TBXA2R | |
| SCHEMBL28122018 | 0.72 | — | — | |
| SCHEMBL19933104 | 0.72 | — | — | |
| SCHEMBL22793232 | 0.72 | LMNA (0.33) | KDM4ELMNAALOX15BLMPMP22 | |
| SCHEMBL16280996 | 0.71 | KDM4E (0.42) | ALDH1A1KDM4EHMGCRCHRM1TBXA2R | |
| SCHEMBL125115 | 0.71 | — | — | |
| SCHEMBL626112 | 0.70 | — | — | |
| SCHEMBL95243 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969230-A | Brominated carbamoyl derivatives useful to impart flame retarding property to combustible substrates | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1976-07-13 | — | — | US | disclosed |