Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | CLK3 | P49761 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11805739 | 0.85 | KDM4E (0.42) | KDM4ERAD52LMNAHTTSMN1; SMN2 | |
| SCHEMBL11803727 | 0.84 | KDM4E (0.40) | KDM4ERAD52LMNAHTTSMN1; SMN2 | |
| SCHEMBL11818281 | 0.83 | KDM4E (0.40) | KDM4ERAD52LMNAHTTSMN1; SMN2 | |
| SCHEMBL11517572 | 0.82 | KDM4E (0.40) | KDM4ERAD52LMNAHTTSMN1; SMN2 | |
| SCHEMBL11813301 | 0.80 | LMNA (0.37) | LMNAHTTSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL11806507 | 0.80 | TDP1 (0.40) | KDM4ERAD52LMNAHTTSMN1; SMN2 | |
| SCHEMBL11814233 | 0.73 | XPO1 (0.30) | — | |
| SCHEMBL11810730 | 0.71 | KDM4E (0.52) | KDM4ERAD52LMNAHTTSMN1; SMN2 | |
| SCHEMBL11805670 | 0.71 | KDM4E (0.42) | KDM4ERAD52LMNAHTTSMN1; SMN2 | |
| SCHEMBL11805651 | 0.70 | CDK9 (0.40) | KDM4ERAD52KMT2AHPGDCDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954438-A | 5-Trifluoromethyl-7-aminobenzimidazoles herbicides | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |