Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 13/20 | 0.42 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11867415 | 0.73 | NOTUM (0.37) | NOTUMCUL4AMAPTKDM4EALDH1A1 | |
| SCHEMBL11817707 | 0.71 | PKM (0.46) | CUL4AMAPTKDM4EALDH1A1MAPK1 | |
| SCHEMBL11248340 | 0.67 | PKM (0.53) | NOTUMALDH1A1MAPK1ARPOLB | |
| SCHEMBL11602223 | 0.66 | NOTUM (0.44) | NOTUM | |
| SCHEMBL16699742 | 0.64 | NOTUM (0.47) | NOTUMMAPK1 | |
| SCHEMBL30100590 | 0.62 | NOTUM (0.46) | NOTUMMAPK1 | |
| SCHEMBL2986241 | 0.62 | NOTUM (0.46) | NOTUMMAPK1 | |
| SCHEMBL1043062 | 0.62 | NOTUM (0.41) | NOTUM | |
| SCHEMBL5085211 | 0.61 | NPC1 (0.43) | NOTUMMAPTKDM4EALDH1A1HTT | |
| SCHEMBL8346712 | 0.61 | NOTUM (0.57) | NOTUMMAPTALDH1A1HTTAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3988455-A | Ditetrazolo(1,5-a:5',1'-c)quinoxalines for control of soil-borne phytopathogens | ELI LILLY AND COMPANY (US) | 1976-10-26 | — | — | US | disclosed |