Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 7/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.35 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30100590 | 1.00 | NOTUM (0.46) | NOTUMIDO1HTR3EHTR3BHTR3A | |
| SCHEMBL11602223 | 0.94 | NOTUM (0.44) | NOTUMIDO1HTR3EHTR3BHTR3A | |
| SCHEMBL16699742 | 0.91 | NOTUM (0.47) | NOTUMIDO1HTR3EHTR3BHTR3A | |
| SCHEMBL1043062 | 0.88 | NOTUM (0.41) | NOTUMIDO1HTR3EHTR3BHTR3A | |
| SCHEMBL11602077 | 0.83 | CYP3A4 (0.46) | NOTUMIDO1HTR3EHTR3BHTR3A | |
| SCHEMBL7272204 | 0.81 | NOTUM (0.42) | NOTUMIDO1HTR3EHTR3BHTR3A | |
| SCHEMBL8462010 | 0.81 | HTR3E (0.41) | NOTUMIDO1HTR3EHTR3BHTR3A | |
| SCHEMBL10830423 | 0.81 | HTR3E (0.38) | NOTUMIDO1HTR3EHTR3BHTR3A | |
| SCHEMBL10493649 | 0.79 | RAPGEF4 (0.43) | NOTUMIDO1HTR3EHTR3BHTR3A | |
| SCHEMBL9244738 | 0.79 | RAPGEF4 (0.43) | NOTUMIDO1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143633-A | Method for preparing 2, 5-dichloro-4-trifluoromethyl aniline | 浙江巍华新材料股份有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-106866426-B | A kind of method of comprehensive utilization for the by-product 2,4,5- trichlorobenzotrifluorides producing 3,4,5-Trichloro-trifluoromethyl-benzene | 浙江巍华化工有限公司 | 2018-08-10 | — | — | CN | claimed |
| CN-106866426-A | A kind of method of comprehensive utilization of the trichlorobenzotrifluoride of accessory substance 2,4,5 for producing 3,4,5 trichlorobenzotrifluorides | 浙江巍华化工有限公司 | 2017-06-20 | — | — | CN | claimed |
| EP-1528052-B1 | Process for the production of 4-amino-3,5-dichlorobenzotrifluoride with high purity commercial products being obtained in parallel | FINCHIMICA SRL (IT) | 2013-07-31 | — | — | EP | claimed |
| CN-101891675-B | Production method of 6-chloro-2-(trichloromethyl)pyridine | DONGYANG YINGRUOHUA GREEN ELECTROCHEMISTRY CO LTD OF HENGDIAN GROUP | 2011-12-14 | — | — | CN | claimed |
| CN-101891675-A | Production method of 6-chloro-2-(trichloromethyl)pyridine | DONGYANG YINGRUOHUA GREEN ELECTROCHEMISTRY CO LTD OF HENGDIAN GROUP | 2010-11-24 | — | — | CN | claimed |
| EP-1528052-A1 | Process for the production of 4-amino-3,5-dichlorobenzotrifluoride with high purity commercial products being obtained in parallel | FINCHIMICA S.p.A. (IT) | 2005-05-04 | — | — | EP | claimed |
| US-4885415-A | HYDROGENATION, DECHLORINATION, CATALYSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-12-05 | — | — | US | claimed |
| CN-106892792-B | Continuous synthesis method and equipment of 3, 4-dichloro benzotrifluoride | 山东道可化学有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-116143633-A | Method for preparing 2, 5-dichloro-4-trifluoromethyl aniline | 浙江巍华新材料股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-116143633-A | Method for preparing 2, 5-dichloro-4-trifluoromethyl aniline | 浙江巍华新材料股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-109970507-B | Continuous production method and continuous production equipment for 3, 4-dichlorobenzotrifluoride | 山东道可化学有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-209901249-U | 3, 4-dichloro benzotrifluoride continuous production equipment | 山东道可化学有限公司 | 2020-01-07 | — | — | CN | disclosed |
| CN-106866426-B | A kind of method of comprehensive utilization for the by-product 2,4,5- trichlorobenzotrifluorides producing 3,4,5-Trichloro-trifluoromethyl-benzene | 浙江巍华化工有限公司 | 2018-08-10 | — | — | CN | disclosed |
| US-7777079-B2 | Preparation method of 2, 6-dichlor-4-trifluoromethyl aniline | ZHEJIANG WEIHUA CHEMICAL CO., LTD. (CN) | 2010-08-17 | — | — | US | disclosed |
| US-20090240083-A1 | Preparation Method of 2, 6-Dichlor-4-Trifluoromethyl Aniline | ZHEJIANG WEIHUA CHEMICAL CO., LTD. (CN) | 2009-09-24 | — | — | US | disclosed |
| CN-101289400-A | Process for synthesizing 2,6- dichlor-4-trifluoromethyl aniline | ZHEJIANG WEIHUA CHEMICAL CO LT (CN) | 2008-10-22 | — | — | CN | disclosed |
| EP-1528052-A1 | Process for the production of 4-amino-3,5-dichlorobenzotrifluoride with high purity commercial products being obtained in parallel | FINCHIMICA S.p.A. (IT) | 2005-05-04 | — | — | EP | disclosed |
| EP-1528052-A1 | Process for the production of 4-amino-3,5-dichlorobenzotrifluoride with high purity commercial products being obtained in parallel | FINCHIMICA S.p.A. (IT) | 2005-05-04 | — | — | EP | disclosed |
| US-4226783-A | OF SIDE CHAINS OF ELECTRONEGATIVELY SUBSTITUTED AROMATIC COMPOUNDS WITH DICHLORINE MONOXIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240083-A1 | Preparation Method of 2, 6-Dichlor-4-Trifluoromethyl Aniline | DCAF7, APOBEC3C, DDT | NOTUM 994/4885IDO1 729/4885HTR3E 2805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.