Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307479 | 0.91 | CTSB (0.67) | CTSBTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL17058720 | 0.89 | CTSB (0.65) | CTSBTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL10526689 | 0.86 | TDP1 (0.74) | CTSBTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL17607327 | 0.84 | CTSB (0.59) | CTSBTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL11781264 | 0.84 | TDP1 (0.50) | CTSBTDP1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL11779011 | 0.82 | CTSB (0.47) | CTSBTDP1ALDH1A1NPC1RAB9A | |
| SCHEMBL5692741 | 0.80 | CTSB (0.54) | CTSBTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL2769398 | 0.79 | CTSB (0.78) | CTSBTDP1ALDH1A1NPC1RAB9A | |
| SCHEMBL589663 | 0.79 | CTSB (1.00) | CTSBTDP1ALDH1A1CYP3A4NPC1 | |
| SCHEMBL7912372 | 0.78 | TDP1 (0.67) | CTSBTDP1ALDH1A1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953598-A | ASTHMA OR RHINITIS TREATMENT | THE UPJOHN COMPANY (US) | 1976-04-27 | — | — | US | disclosed |