Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 15/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.66 |
| ▸ | HTR2A | P28223 | 2/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.66 |
| ▸ | MLNR | O43193 | 1/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.66 |
| ▸ | DRD1 | P21728 | 1/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.66 |
| ▸ | MC3R | P41968 | 1/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.66 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.66 |
| ▸ | GHSR | Q92847 | 1/20 | 0.66 |
| ▸ | ADRB3 | P13945 | 14/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23012291 | 1.00 | ADRB2 (0.66) | ADRB2ADRB1SLC6A2HTR2ASLC6A4 | |
| SCHEMBL22035288 | 0.83 | ADRB2 (0.69) | ADRB2ADRB1SLC6A2HTR2ASLC6A4 | |
| SCHEMBL23931055 | 0.81 | ADRB2 (0.64) | ADRB2ADRB1SLC6A2HTR2ASLC6A4 | |
| SCHEMBL23012741 | 0.81 | ADRB2 (0.47) | ADRB2ADRB1SLC6A2HTR2ASLC6A4 | |
| SCHEMBL14119565 | 0.81 | ADRB2 (0.47) | ADRB2ADRB1SLC6A2HTR2ASLC6A4 | |
| SCHEMBL928189 | 0.80 | ADRB2 (1.00) | ADRB2ADRB1SLC6A2HTR2ASLC6A4 | |
| Vilanterol SCHEMBL15614685 | 0.80 | ADRB2 (1.00) | ADRB2ADRB1SLC6A2HTR2ASLC6A4 | |
| SCHEMBL17031687 | 0.80 | ADRB2 (1.00) | ADRB2ADRB1SLC6A2HTR2ASLC6A4 | |
| Vilanterol SCHEMBL142630 | 0.80 | ADRB2 (1.00) | ADRB2ADRB1SLC6A2HTR2ASLC6A4 | |
| Vilanterol SCHEMBL29623445 | 0.80 | ADRB2 (1.00) | ADRB2ADRB1SLC6A2HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131582-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR MEDIATED DISEASES | Vertex Pharmaceuticals Incorporated (US) | 2017-02-22 | — | — | EP | disclosed |
| WO-2015160787-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR MEDIATED DISEASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2015-10-22 | — | — | WO | disclosed |
| EP-2749283-A2 | Combination of glycopyrronium and olodaterol | Cipla Limited (IN) | 2014-07-02 | — | — | EP | disclosed |
| EP-2651891-A1 | BICYCLIC RING SYSTEM SUBSTITUTED AMIDE FUNCTIONALISED PHENOLS AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2013-10-23 | — | — | EP | disclosed |
| EP-2651932-A1 | BICYCLIC RING SYSTEM SUBSTITUTED SULFONAMIDE FUNCTIONALISED PHENOLS AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2013-10-23 | — | — | EP | disclosed |
| EP-2245026-B1 | SPIROCYCLIC HETEROCYCLES, MEDICAMENTS CONTAINING SAID COMPOUNDS, USE THEREOF AND METHOD FOR THEIR PRODUCTION | BOEHRINGER INGELHEIM INT (DE) | 2012-08-01 | — | — | EP | disclosed |
| WO-2012080457-A1 | BICYCLIC RING SYSTEM SUBSTITUTED SULFONAMIDE FUNCTIONALISED PHENOLS AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012080456-A1 | BICYCLIC RING SYSTEM SUBSTITUTED AMIDE FUNCTIONALISED PHENOLS AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |
| EP-2424603-A1 | INHALATION DEVICE | Boehringer Ingelheim International GmbH (DE) | 2012-03-07 | — | — | EP | disclosed |
| EP-2408571-A2 | RESERVOIR AND ATOMIZER | Boehringer Ingelheim International GmbH (DE) | 2012-01-25 | — | — | EP | disclosed |
| EP-1941263-A1 | OPTICAL SEMI-QUANTITATIVE 100 % FILLING CHECK OF PHARMACEUTICAL CAPSULES ON CAPSULE FILLING MACHINES | Boehringer Ingelheim International GmbH (DE) | 2008-07-09 | — | — | EP | disclosed |
| WO-2008034506-A1 | PISTON DOSING PUMP | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-03-27 | — | — | WO | disclosed |
| WO-2007141203-A1 | ATOMIZER | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-12-13 | — | — | WO | disclosed |
| WO-2007128381-A1 | ATOMIZER AND METHOD OF ATOMIZING FLUID | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-11-15 | — | — | WO | disclosed |
| WO-2007118342-A2 | MEDICAMENT CARRIER FOR AN INHALER, AND MULTIDOSE POWDER INHALER | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007118858-A1 | INHALER | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007118648-A1 | INHALER | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007062726-A2 | DISPENSING DEVICE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007062745-A2 | INHALER AND STORE FOR A DRY MEDICAMENT FORMULATION AND RELATED METHODS AND USE THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007045670-A1 | OPTICAL SEMI-QUANTITATIVE 100 % FILLING CHECK OF PHARMACEUTICAL CAPSULES ON CAPSULE FILLING MACHINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-04-26 | — | — | WO | disclosed |