Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11122497 | 0.98 | ZDHHC20 (0.39) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL10841309 | 0.92 | CA12 (0.36) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL10830508 | 0.89 | ZDHHC20 (0.35) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL11116095 | 0.87 | ZDHHC20 (0.36) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL11119883 | 0.84 | DNM1 (0.39) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL11817931 | 0.77 | CA12 (0.32) | CA12CA1CA9CA2 | |
| SCHEMBL1793489 | 0.73 | EPHX1 (0.47) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL1796143 | 0.73 | EPHX1 (0.47) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL1794229 | 0.73 | EPHX1 (0.47) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL2954535 | 0.72 | CA12 (0.42) | ZDHHC20ZDHHC2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3996232-A | ANTIULCER AGENTS | WILLIAM H. RORER, INC. (US) | 1976-12-07 | — | — | US | disclosed |