SCHEMBL11815134

SCHEMBL11815134

O=C(O)c1nc2c(O)cccc2c([Hg]c2ccccc2)c1[Hg]c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.42
KDM4E B2RXH2 5/20 0.41
L3MBTL1 Q9Y468 4/20 0.41
KDM4A O75164 2/20 0.41
EGLN1 Q9GZT9 2/20 0.41
RAB9A P51151 2/20 0.41
HIF1AN Q9NWT6 1/20 0.41
PARP1 P09874 3/20 0.40
TNKS O95271 2/20 0.40
TNKS2 Q9H2K2 2/20 0.40
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 3/20 0.38
LMNA P02545 1/20 0.38
ALOX12 P18054 1/20 0.38
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
CCR6 P51684 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6079912 0.73 ESR1 (0.50) CYP1A2KDM4EL3MBTL1KDM4AEGLN1
SCHEMBL6079956 0.71 KDM4E (0.44) CYP1A2KDM4EL3MBTL1KDM4AEGLN1
SCHEMBL6080384 0.71 KDM4E (0.46) CYP1A2KDM4EL3MBTL1KDM4AEGLN1
SCHEMBL11118380 0.69 KDM4E (0.79) CYP1A2KDM4ERAB9AKMT2AALDH1A1
SCHEMBL11118383 0.69 KDM4E (0.79) CYP1A2KDM4ERAB9AKMT2AALDH1A1
SCHEMBL6080749 0.69 CYP1A2 (0.54) CYP1A2KDM4EL3MBTL1KDM4AEGLN1
SCHEMBL3246366 0.68 KDM4E (0.47) CYP1A2KDM4EL3MBTL1KDM4AEGLN1
SCHEMBL13313361 0.67 CYP1A2 (0.60) CYP1A2KDM4EL3MBTL1KDM4AEGLN1
SCHEMBL6080440 0.66 P2RX3 (0.44) CYP1A2KDM4EPARP1ALDH1A1CYP2D6
SCHEMBL7968125 0.65 ACHE (0.59) CYP1A2KDM4EL3MBTL1KDM4AEGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3998808-A INSECTICIDES, FUNGICIDES VELSICOL CHEMICAL CORPORATION (US) 1976-12-21 US disclosed
US-3948967-A HERBICIDE, FUNGICIDE VELSICOL CHEMICAL CORPORATION (US) 1976-04-06 US disclosed