Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11815803 | 0.88 | POLB (0.49) | POLBCNR2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11819779 | 0.87 | MAPK1 (0.44) | MEN1KMT2AMAPK10LMNAALDH1A1 | |
| SCHEMBL11816576 | 0.87 | MAPK1 (0.44) | MEN1KMT2AMAPK10LMNAALDH1A1 | |
| SCHEMBL11816190 | 0.87 | MAPK1 (0.44) | MEN1KMT2AMAPK10LMNAALDH1A1 | |
| SCHEMBL11819697 | 0.86 | MAPK1 (0.45) | MEN1KMT2AMAPK10LMNAALDH1A1 | |
| SCHEMBL11817256 | 0.86 | LMNA (0.48) | POLBCNR2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11825260 | 0.84 | ACMSD (0.44) | MEN1KMT2AMAPK10LMNAALDH1A1 | |
| SCHEMBL11822423 | 0.84 | LMNA (0.42) | CNR2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11822989 | 0.83 | MEN1 (0.44) | MEN1KMT2AMAPK10LMNAALDH1A1 | |
| SCHEMBL11825265 | 0.83 | MEN1 (0.44) | MEN1KMT2AMAPK10LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3960868-A | Derivatives of 6,7 or 8 cycloalkyl 4-oxo quinoline 3 carboxylic acid | CIBA-GEIGY CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |